The device “ECOSVET 1” for professionals

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The device is designed to stimulate the nonspecific protection of cellular and humoral immunity, provide general strengthening and anti-inflammatory effects, is indicated for a number of common diseases (see the Instructions for medical use). Due to the pulsed effect in a short period of time, UV radiation practically does not cause erythema.

The device and the method of treatment implemented by it are patented in Russia by Yu.M.Belyaev (Ph.D., Doctor of Economics, Professor, corresponding Member of the Russian Academy of Sciences). The mechanism of action of the pulse effect of the device “Ecosvet1”, we have studied together with a number of medical institutions for more than 20 years, the results are presented in the attached Conclusions. It has been experimentally confirmed with confidence that the device has a restorative and anti-inflammatory effect, stimulating the nonspecific protection of cellular and humoral immunity. The device implements a new method of treatment and prevention in world practice: noninvasive polychromatic light pulse therapy (NPSIT). Systemic clinical studies of the method were first conducted by N.K.Starkov in his PhD thesis (Krasnodar, KubSMU, 2000, “Noninvasive quantum therapy in the complex treatment of purulent-inflammatory surgical diseases — clinical and experimental studies”).
The mechanism of action and the achieved effect are provided by using the pulse mode of the UFO simultaneously in 2 parts of the UV range (A, B), as well as, partially, in the visible and infrared wavelength ranges (less than 1%). As in the case of laser radiation (Kochetkov A.V., Moskvin S.V., 2004), UFO in pulsed mode is much more effective than continuous due to the trigger effect on the body: it triggers local and generalized reactions and processes that are aimed at restoring the impaired functions of organs and tissues, at restoring local damage (systemic adaptive reaction of a living system with its various manifestations at all levels of life -Ulashchik V.S., 2008). The trigger effect, according to Gurevich K.Ya., Kostyuchenko A.L., Belotserkovsky M.V. Kholmogorov V.E., is the development of chain free radical reactions that explain such rapid photomodification of blood. UV radiation leads to the formation of free radicals of aromatic and sulfur-containing proteins, pyrimidine bases of nucleic acids. Radicals of this type take part in the transfer of electrons in the respiratory chain of mitochondria; such radicals occur, for example, in the interaction of phenolic antioxidants with free radicals of lipids. Free radical oxidation of lipids plays a leading role in many effects of UV irradiation (Kozinets G.I.). According to Chalenko V.V., Medvedev A.N., Rakovschik D.G. (1992) physiological photoeffects according to the degree of exposure can be conditionally divided into the following groups:
1. The effect of UFOC on individual biologically active substances of blood plasma, that is, the molecular effect;
2. The effect of UFOC on the functional systems of blood plasma;
3. The effect of UFOC on blood cells and their function;
4. The effect of UFOC on whole blood and its components.

The clinical effectiveness of UFOC is due to the immunoregulatory effect (Samoilova K.A., 1989). However, the direct effect of UFOC on immunocompetent cells and various aspects of their functional state have not been sufficiently studied. According to Ashinov N.A. (1999), after UFOC, there are changes in the expression of differentiation receptors CD3, CD5 and CD8-receptors of lymphocytes, the expression of markers of activation of CD25 and DR-antigen lymphocytes decreases, the production of IL-1, TNF increases. The mechanism of action of UFOC is due to stimulation of immunity and action on bacteria, removal of medium-molecular proteins from the body, reduction of arterial hypoxemia, improvement of oxygen transport function of erythrocytes and activation of redox processes (Vetchinnikova O.V., 1995; Kostyuchenko A.L., 2000; Tatarchenko I.P., Komarov V.T., 2001). Ultraviolet irradiation activates erythro- and leukopoiesis, increases the nonspecific resistance of the body. The identity of biological effects when exposed to the blood of UFOs, helium-neon laser and daylight was shown in the works of K.A.Samoilova (1989) and V.I.Karandashov (1989-2001) et al.(which, in particular, is explained by the loss of the main advantage of laser radiation-coherence- when it enters the tissues of the skin). The difference in the mechanisms of action at the molecular and cellular levels is due (at close values of radiation intensity) mainly to the difference in spectral and frequency characteristics. The main therapeutic effects of long-wave UFO (DUF) are immunostimulating and photosensitizing effects (Bogolyubov V.M., Ponomarenko, 1998), however, in the case of pulsed exposure with a pulse length of no more than 0.001 s, the pigment-forming effect characteristic of continuous irradiation of DUF is absent, because at such a duration biochemical processes with the formation of melanin “do not have time” happen. In addition, UFO causes a change in the functional state of the central nervous system and the cerebral cortex: there is an improvement in blood circulation, increased secretory activity of digestion and metabolism (Ulashchik V.S.). The main therapeutic effects of medium-wave UFO (SUF) with a suberythemic amount of radiation: vitamin-forming, immunomodulatory, anti-inflammatory, analgesic. Due to the wide spectrum of radiation, similar to solar radiation in the UV region, the mechanism of action is the most physiological. Due to the trigger effect (the “inclusion” of the body’s defenses to the action of an external stimulus), an improvement in the functional state is observed in organs that are not directly exposed to radiation. Taking into account the frequency characteristics of the organism, as well as the spectral adaptation of the light pulse radiation, can significantly enhance the effect of exposure.

It should be noted that, as in the case of laser exposure, none of the existing hypotheses fully reveals the mechanism of biological reaction to pulsed polychromatic light irradiation. For example, it would be interesting to investigate the “resonance hypothesis”, which may be based on the effect of the so-called “mitogenetic radiation” known for about 90 years (Gurvich, 1923).

At the same time, NPSIT has significant advantages over laser radiation: a wide spectral range, adapted to the body and blood by spectral characteristics, more effective; higher energy capabilities (especially in hemodynamic therapy); non-invasiveness, safety, shorter duration of the procedure.

The ability to affect any part of the patient’s body surface with a wide light beam is provided by a remote emitter unit connected to the control unit by a long flexible wire. The emitter is made in the form of a flashlight, which is easily located in the hand.

The device is intended for use in conditions of medical, therapeutic and preventive and research medical institutions. Application- areas of medicine- according to indications. On the recommendation of a doctor, it is possible to use it at home.

The main indications for use: 1) in outpatient and sanatorium-resort practice — chronic inflammatory diseases of internal organs, diseases of the musculoskeletal system, metabolic disorders, cardiovascular, allergic, infectious diseases, chronic fatigue syndrome, etc.; 2) in dermatology — psoriasis, eczema, seborrhea, phlegmon 3) in surgical practice — purulent inflammatory diseases, acute inflammatory diseases of internal organs, sluggish ulcers and wounds.

Contraindications (almost the same as with traditional UFOs in physiotherapy): hypersensitivity to UFOs, porphyria, thrombocytopenia, hypocoagulation, acute cerebral circulatory disorders, liver and kidney diseases with severe dysfunction, hyperthyroidism, systemic lupus erythematosus; autoimmune diseases. Preparations with photosensitizing effect, which should usually be excluded when exposed to UV:

— Antibiotics: dimethylchlortetracycline, nalidixic acid, sulfonamides.

— Antifungal drugs: griseofulvin;

— Antihistamines: promethazine;

— Diuretics: thiazide;

— Dyes: eosin;

— Flavoring substances: musk, 6- methylcoumarin;

— Furocoumarins: psoralen;

— Hypoglycemic drugs: chloropamide, tolbutamide;

— Tranquilizers: chlorpromazine, trifluoperazine.

As follows from the conclusions of medical organizations, the results of treatment are: improvement of blood test parameters (both general and immune), improvement of rheological properties of blood, increase and restoration of the immune status of the body, strengthening of redox and reduction of inflammatory processes, reduction of allergic reactions, triggering the mechanism of production of its own gamma interferon in the body. The chief scientific consultant of the research is the head of the Department of Restorative Medicine, Balneology and Physiotherapy of the Kuban State Medical University. Corresponding Member of the Russian Academy of Medical Sciences, MD, Professor A.T.Bykov, under whose leadership immunological studies were conducted and the possibility of using the method in restorative medicine was proved. Research continues.

Extensive experience in the treatment of skin diseases (for example, psoriasis) using the device “Ecosvet 1” has been accumulated by Doctor of Medical Sciences, Professor F.Ya.Khairulin (research continues). Medical research was carried out at the departments of KubSMU: general surgery (Head of the Department-MD, Prof. Yu.P.Savchenko); propideutics of internal diseases (MD, Professor A.S. Adamchik) and on the basis of Krasnodar City Clinical Hospital No. 1; at the Department of Clinical Immunology, Allergology of KubSMU and CJSC “Center Allergies and Immunology” — Head of the Department and Director of the Center – MD, Prof. R.A.Khanferyan, etc.

In addition, studies of the device have been conducted (and are being conducted) in a number of central medical organizations of the country: in the Moscow Center for Biochronotherapy (Professor V.A.Borisov); in the Testing Center and the Certification Body for Medical Devices of the Federal State University “NIIT and IO Rosmedtechnology” (expert opinions approved by the Academy. RAMS V.I.Shumakov and corresponding Member of the RAMS, S.V.Gauthier); FSU VNIIMT Roszdravnadzor (MD, professor Yu.K.Larionov); Research Institute of Medical Primatology (akadem. RAMS B.A.Lyapin). Currently, the research of the “Ecosvet” apparatus is carried out: at the Federal State University “Russian Scientific Center for Restorative Medicine”; at the Department of Infectious Diseases of KubSMU, etc.

Today, the devices “Ecosvet1” are already successfully operating in a number of sanatoriums of the Krasnodar Territory and the city of Esentuki, in polyclinics of Krasnodar (including in JSC “TSVMR Krasnodar Balneotherapy”). There is a successful experience of using the device at home.

The conclusions of experts indicate that the use of the device as an immunity stimulator has a broad perspective – both in the treatment and prevention of common diseases (including seasonal ones, such as influenza). Oncology (photodynamic procedure with the use of UV-radiation sensitizers), as well as allergology, dermatology, ophthalmology, gynecology, endocrinology, infectious, including viral, diseases, etc. are predicted to be one of the promising areas of application of the method.

Upon additional request, it is possible to develop modifications of the device for any conditions, including for use in medical vehicles, in the field, on board a ship, etc.